In this week's episode we’ll discuss the effects of voxelotor on cerebral blood flow in pediatric sickle cell disease, learn more about venous and arterial thrombosis in patients with Vexas syndrome, and discuss differential sensitivity to tyrosine kinase inhibitors in ABL-class acute lymphoblastic leukemia. 

Featured Articles:

• The influence of voxelotor on cerebral blood flow and oxygen extraction in pediatric sickle cell disease 
• Venous and arterial thrombosis in patients with VEXAS syndrome 
• Tyrosine kinase inhibitor response of ABL-class acute lymphoblastic leukemia: The role of kinase type and SH3 domain