Karla was last seen at approximately 7:00 p.m. on October 20, 1999 in the 800 block of Bonita Avenue in Las Vegas, Nevada. She went to visit a neighbor's son to play with him, but the neighbor told her to go home because it was getting late. She played outside alone for about fifteen minutes before leaving on her bike.

The location was two blocks from her family's home and also near the Stratosphere Tower in downtown Las Vegas. Karla never returned to her house and has not been seen again.

She wasn't reported missing until the next morning. Her father spoke to the neighbor who saw Karla, assumed she must have gone to another friend's house, and went home to bed. The next morning, when she still wasn't home, her mother called the school to see if she'd gone there for classes. The school principal called the police at this time.

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