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How hot is too hot for human health?

How hot is too hot for human health?

Released Tuesday, 11th July 2023
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How hot is too hot for human health?

How hot is too hot for human health?

How hot is too hot for human health?

How hot is too hot for human health?

Tuesday, 11th July 2023
Good episode? Give it some love!
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Episode Transcript

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1:00

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1:08

Somebody tells me there's going to be another heatwave. I think there's probably

1:11

going to be a lot of heatwaves. Crystal

1:14

ball time, isn't it?

1:19

Hello there and welcome to Inside Health. I've

1:21

come to Cardiff Bay because it has been

1:24

a red hot day, sun beating down the

1:26

whole time. But

1:28

here, by the water, there's a lovely

1:31

cooling breeze. We're

1:34

going to spend this programme trying to figure

1:36

out how hot is too hot for the human body. Because

1:39

with constant headlines of global

1:41

warming and rising temperatures all

1:43

around the world, it's an issue I think we need to

1:45

get to grips with. So I'm going to start

1:47

off by finding out what people

1:49

here think about the temperature. Do

1:53

you have two minutes to talk about the weather? Weather? Yeah,

1:55

really easy question. What

1:57

temperature's too hot? For me, never.

1:59

It's beautiful. Never. I

2:02

think like 28 is probably the peak of what

2:04

I can handle. I'd say like 33, 34 is like hot.

2:08

What happens to both of you when you get into like

2:10

the mid-30s? Smell into a puddle. Yeah, totally.

2:13

More than 20s, sound a bit iffy then. Oh,

2:16

God. I'd be

2:18

blocked away in the nice breeze or somewhere.

2:21

What happens to you when it's too hot? Oh, I'm big and hairy

2:23

so I sweat. About 50 degrees. About 50? Yeah,

2:26

yeah. I've been to Turkey

2:28

last year and it was 50.

2:31

Yeah, we had to go in then. I understand.

2:34

We don't mind it like this. It's got a little bit of a breeze. It makes everybody

2:36

happy, doesn't it? I'll be honest, I don't think I agree with 50

2:45

degrees. That

2:47

sounds way too hot for me, especially I've got

2:49

to work on that day. In a minute, we're

2:51

going to test my body in the laboratory

2:53

and see what it can cope with. But first,

2:56

I wanted to know what kinds of temperatures we're going to

2:58

have to deal with in the future.

2:59

Hello, I'm Professor Lizzie Kendon.

3:02

I'm strategic head of understanding

3:04

climate change at the Met Office Hadley Center.

3:07

Well, Lizzie, thank you for coming on. Must be a very busy

3:09

time at the Met Office. Not

3:11

that long ago we had the hottest June ever in the

3:13

United Kingdom. Is that a taste of what's to come?

3:16

So

3:16

it's not just been the warmest June on record. Last

3:18

year was the warmest year for the UK

3:21

and we have actually had a whole series of records.

3:23

In July last year, we reached 40

3:26

degrees C for the first time in the UK, which

3:28

absolutely smashed all previous records.

3:30

I really notice it just like in the space

3:32

of my near full decades of life.

3:35

I think that the summers now feel nothing like

3:37

they did when I was a child.

3:39

Our climate is changing. I think it's really important

3:41

to realize it's no longer just something that's

3:43

distant or far away from us or something in

3:45

the future. I think we are really seeing it now

3:48

here in the UK, you know, exceeding 40 degrees

3:50

C. That was practically impossible

3:53

had it not been for climate change. And as

3:55

we move into the future, these sort of temperature

3:57

extremes that we've experienced will become increasingly...

3:59

the common occurrence. Will they become

4:02

normal? I mean isn't that almost the

4:04

big question here kind of like what is our future

4:07

hot temperatures and summer going to be for us in the UK?

4:10

We do expect something like the hottest summer day

4:12

to increase by six degrees C

4:14

under a high emission scenario so that is a

4:16

huge increase by the end of the century but

4:19

you know the path that we follow is

4:21

not defined now it's in terms

4:23

of how we act over the coming years

4:26

is so very critical. Lizzie

4:27

thank you so much for coming on and explaining all that.

4:29

Thank you.

4:34

Well now I've come to the University of South

4:36

Wales to meet Professor Damian Bailey and

4:39

regular Inside Health listeners will remember

4:41

Damian from checking

4:43

me in a really cold room and we're going to do the opposite

4:46

today and go somewhere really

4:48

warm to see what the reaction is in my body

4:51

so Damian hi. Morning

4:53

James good to see you again. Lovely sunny day both

4:55

of us in shorts and t-shirts start contrast for the

4:57

last time I was here. Well it's like this every day

5:00

in Wales of course beautiful sunny day and

5:02

yeah we're going to be heating you up today

5:03

so it's going to be a lot warmer inside

5:06

than it is outside. Wow how

5:08

tempting that sweaty morning let's get on with

5:10

it. Great.

5:14

Okay James here we are we're in

5:16

front of the environmental chamber it's where

5:19

you were a few months ago but of

5:21

course you're exposed to cold heat today. Okay

5:24

what temperatures are we aiming for? So we're aiming for 35 degrees

5:26

centigrade 50 relative

5:29

humidity and we'll push it to 40 degrees

5:31

centigrade at the end of the exposure so typical

5:33

temperatures and humidities we'd encounter during a

5:36

heat wave. So we're going to go in and hopefully find

5:39

or get close to an answer for how hot is too hot

5:41

for the human body what are the changes that take place

5:44

when we're subject

5:44

to high temperatures and it just feels like it's a really important

5:47

question now doesn't it Damian because you can't

5:50

really escape news about how our climate

5:52

is changing and how things getting hotter. This

5:54

is becoming the new norm so absolutely

5:57

agree you know understanding the physiology and the counter

5:59

measures.

5:59

to try to prevent these changes,

6:02

you know, is essential. Shall we

6:04

go in? Yep, follow me, James. You're

6:07

up for view. I'll

6:11

just close the door. Okay,

6:14

so first thing I'm noticing is quite cool

6:16

in here, certainly compared with outside. So

6:18

it's thermonutral at the moment, 21 degrees centigrade

6:21

and 50% relative humidity. It's

6:23

like steel walls all the way around really

6:25

heavy doors, small little portholes looking

6:28

out into the rest of the world. It really does

6:29

remind me of an oven bin. Well,

6:32

it's probably not gonna be quite as hot as an oven,

6:34

but you will be sweating

6:36

and the body, the physiology is gonna change

6:38

quite considerably during the exposure. Well, I'm in

6:40

my lycra, ready to go. Short

6:43

some T-shirts, what's first? So

6:45

the very first thing that we need to test is

6:47

your metagenastics, your cognitive

6:49

ability. So this is short-term memory

6:52

and I'm gonna give you a list of 15 words. I'm

6:54

gonna say them out slowly and then

6:57

at the end of it, I want you to

6:59

repeat as many

6:59

of those words as you can possibly

7:02

remember. This is where I wish I'd done one of those how

7:04

to memorize sequences kind

7:07

of exercises. Okay, so you're

7:09

ready to go? I'm ready to go. So listening into

7:11

these 15 words. Drum, curtain,

7:15

bell, coffee, school.

7:19

["The Little Mermaid")

7:22

Turkey, house,

7:26

river. Okay, James, as many as you can

7:28

recall. Bell, is

7:30

that right? I

7:33

didn't know if I can remember the beginning. I've

7:35

got one. Curtain,

7:37

drum. I

7:40

do, this is terrifying. Grimber, farmer

7:42

and nose, house. Because

7:46

clapping my hands is gonna help me remember. No,

7:50

I'm done. Fantastic, well done, James, that was the first

7:52

part. I feel I need to warn you that I'm a naturally

7:54

quite sweaty person. In fact, sweating

7:57

in this environment, as you will find out, is

7:59

a good thing.

7:59

Okay James, so the first thing we need

8:02

to do is to get a fighting weight on

8:04

you. We want to measure your body mass.

8:06

So you've got shorts and boat

8:08

shoes and a lycra top on. What

8:10

I'd like you to do is to, behind the screen... Another

8:13

fashion week, here I come, right? Absolutely.

8:16

Strip everything off. Okay, can

8:18

I pass you my microphone? Sure. There you go.

8:21

The closer we can get to a

8:23

nude body mass, the better

8:26

when it comes to calculating sweat rates. Your

8:28

eyes only. And then when you're ready, stand

8:31

on the scales. I am on.

8:33

Test error 12. You're

8:36

kidding me. If you could just jump off

8:38

again. Yeah. And

8:41

then jump back on again. How much do you need?

8:45

88 points. It's all about the guns, right? Okay,

8:50

you can get yourself dressed

8:51

again. We're going to set you up with

8:53

all of the different bits of kit that

8:55

will allow us to make the measurements that we're going to make. Why

8:57

am I going to be wired everywhere? You will

8:59

be connected to the National Grid, but we'll be making

9:01

all sorts of measurements. So again,

9:03

we're interested in how the cart,

9:06

how the lungs, how the brain and

9:08

the muscles, how all of these organ systems

9:11

communicate to one another, and how the body

9:13

then responds to that heat stress. Let's

9:15

find out. Great. Okay, take a seat.

9:19

Just relax. Do you mind if I take your

9:21

glasses? We'll put

9:23

a headset on. We're going to measure how

9:25

quickly the blood is rushing into your

9:28

brain. By the way, that funny noise in the

9:30

background was gel being put onto

9:33

the ultrasound probe. So it might feel a bit

9:35

cold. Gooey. Yeah.

9:38

Yeah. You got me. We

9:43

got a tissue there. There's a bit on the microphone

9:45

here.

9:46

We're all squashed.

9:52

Okay, James, so you can hear that pulsatile

9:54

whoosh whoosh. It's a fabulous sound.

9:57

So you've just strapped a black box onto my own.

9:59

It's a little black box, so this

10:02

is known as a finger photo-pleth-mismograph.

10:05

So finger photo-pleth-mismograph. That's a big word. So

10:08

this is allowing us to measure beat

10:11

by beat arterial blood pressure.

10:13

From that, we're also going to assess

10:16

how much blood in liters per minute

10:19

is moving around your body. So that's known as your

10:21

cardiac output. Okay, so

10:24

we're placing the sticky electrodes

10:26

onto you now, James. So this is going to allow us to measure

10:28

your heart

10:29

rate in beats per minute. Blood

10:32

pressure is working nicely. Heart rate is working

10:34

nicely. All of the physiological

10:37

signals at the moment are telling me that you're in

10:40

spiffing shape. Okay, James.

10:42

So I'm going to pass you this mouthpiece.

10:45

So it looks a bit like a scuba diving

10:47

mouthpiece. It's going to allow us to calculate

10:50

oxygen uptake and carbon dioxide

10:52

output. And from that, we can determine

10:55

what types of fuels your body

10:57

is burning. Okay. There

10:59

you go.

10:59

Okay, so we're going

11:02

to do... Change the TUTA, James. I

11:04

didn't understand a word you said. But

11:06

James, what I'm going to ask you to do now is

11:08

just close your eyes nice

11:10

and relaxed. Give

11:13

me a left-hand thumbs up if you're okay. That's

11:16

great. Nice and relaxed. Try not to speak

11:18

and keep your head nice and

11:20

still.

11:21

Brilliant,

11:23

James. I'm going to place this into

11:25

your earlobe and I'm

11:28

going to get a temperature. Okay.

11:30

Everything that we need from you now we've collected in

11:33

the control condition. Well, I don't think I can go

11:35

very far at the moment, Damon, because I'm properly wired up

11:38

head to toe. So I've got a headpiece on.

11:40

I've got things all down my arm. Little

11:43

sensors plugged in and sellotaped to my body

11:45

all over the place. I'm going to dread taking those off

11:47

my hairy chest later, I think. So I'm a bit stuck here.

11:49

So subject me to your worst.

11:52

First I'm about to get the fans

11:52

on so you hear them kicking in

11:55

any minute. There we go. So what do I

11:57

have to do? Just sit and sweat. So

12:02

we've

12:02

gone from 21 degrees James, we're

12:04

currently at 23 degrees, all route to 35. It's

12:10

only gone up two but it's starting to go warm.

12:13

Absolutely.

12:19

So we're at the temperature that

12:21

we have targeted so we're at 35 degrees

12:23

centigrade now James. I'm feeling a little bit sweaty

12:25

under the armpits. Yeah. I'm

12:28

afraid to get off the seat. Okay,

12:30

we're going to stop the fast.

12:34

Okay James, so how are you feeling at the moment? Not

12:36

too bad. Like it is warm, I know that

12:38

it's warm but I'm just sat in the chair not doing anything

12:41

so it's kind of like I can feel like I can cope with this.

12:44

I can see the sweat. I wouldn't want to work in this temperature

12:46

though. Yeah and as you say you're doing nothing

12:48

you're... I think I'm glistening. I

12:50

think that's the word, bounce yes. What's

12:52

that noise? It's expansion there because everything's

12:54

been heated up. We can already see some of the

12:56

signs of what our bodies are doing in here. Just

12:59

the sweat. So you've got the evaporative heat

13:02

loss. You've also got a convective heat

13:04

loss so your skin is like

13:06

mine as well, it's a little bit redder. So

13:08

you've got what we call peripheral vasodilation

13:11

so those blood vessels have opened up just to try

13:13

to get blood to the periphery so that you're getting a

13:15

little bit colder. The thermostat

13:17

in the brain, the hypothalamus is

13:20

constantly tasting the temperature

13:22

to which you're exposed to and it sends

13:24

out all of these signals which we'll be measuring to

13:26

try to maintain homeostasis, to maintain

13:29

that comfortable set point. Okay James

13:31

so what we're going to do now is we're going to repeat all

13:33

of

13:34

the measurements we did in the control condition

13:36

now in the hot. So this is your

13:38

favorite part, this is the mental agility. Oh

13:40

not the words one. Again it's the

13:43

words so I'm going to ask you to recall 15 words.

13:46

Good to go. Good to go. Drum.

13:50

All I can feel is my body sweating. I can't even remember

13:52

if I've already said house, this is how badly I'm doing. You've snowed,

13:54

you haven't said house? Mmmhmm.

13:59

I think I've already said house.

13:59

I said turkey but I'm gonna say turkey again because I

14:02

feel like a roasted turkey right now. It's

14:04

gonna annoy me but I'm done. Good job, well

14:06

done, fantastic. Okay, so.

14:08

I'm feeling the heat now. You know when you see it was 35,

14:11

I was like, is it really, does it feel that bad? And now

14:13

I've been sat in it for longer, I'm starting

14:15

to go a bit melty now. Just creeps up

14:17

on it, isn't it? Yeah, my microphone's quite

14:19

slippy. So nice and relaxed,

14:22

so eyes closed as we make these

14:24

measurements and psychologically just preparing

14:27

yourself for an extra five degrees centigrade

14:29

to come as well. Thanks for

14:32

that. So we've collected

14:35

all of the information

14:39

that we need to collect now at 35 degrees centigrade.

14:41

We're all sweating. Shall we take it up to 40.3

14:44

degrees centigrade which was the hottest day

14:47

the UK's ever had? Absolutely, do you wanna go for it?

14:49

Let's try it. Okay. Because the

14:51

first time wasn't bad enough. Okay, right,

14:54

so we're gonna get the fans on again and

14:57

we're gonna take it up another 5.3 degrees.

15:05

Okay, James, so

15:07

we're at temperature now, the target. This

15:10

is 40 degrees centigrade, how does it feel? Brutal,

15:12

this is no longer pleasant. It just feels like it's

15:15

pounding on me now. Okay, so we're gonna

15:17

stop the fans and we're gonna repeat all of

15:19

the measurements again. Why am I feeling it

15:21

more now, Damien, than at 35? Because

15:24

we went from 20 to 35 and it's kind of

15:26

like okay, we're going from 35 to 40 and I'm kind of,

15:29

oh. It's just making it so much harder

15:31

for you to lose heat. I'm gonna need a very big towel

15:33

sometimes here. And a big

15:35

shower, I'd say. Yes. Okay,

15:41

James, so that's us, we're finished.

15:43

So we're gonna bring some cool air in now. Oh yes,

15:45

yes, bring me the cup. I

15:47

think we need to, we always do

15:50

sterilize the equipment at the end of this experiment before

15:52

we... Yeah, I feel sorry for whoever

15:54

has to use this next. All good? Yep.

15:57

Oh. Well done, how do you

15:59

feel?

15:59

I was surprised at the difference between 35 and 40. Both

16:03

feel very hot, but it was

16:05

a world of difference in terms of how it felt.

16:08

Sometimes it's

16:10

not linear, it's exponent, you know, it just gets, just

16:12

for that 5 degrees centigrade, it doesn't sound

16:14

much, but it really is physiologically so

16:17

much more of a challenge. One of the things I was thinking the whole

16:19

time in there was like, where is all of my

16:21

sweat going? I think we've

16:23

all been breathing it in. Yep, you

16:25

left a little puddle there. A

16:28

lot of it has

16:29

been absorbed into your clothes of course, but

16:32

we'll be taking all of those

16:34

off again and getting a new body mass, a

16:37

post-exposure body mass on you so that we can calculate

16:39

the sweat rates. Right, back behind the curtain. Well,

16:42

why don't you sweat down, James? I've got some roll

16:44

here. Thank you. So we want

16:46

to try to take as much of that

16:48

sweat off the way as possible.

16:51

Over as possible, yeah. And just throw it on the

16:53

floor, James, that's fine. And who wants this at the end

16:55

of the day? I don't know why producer Jerry is refusing

16:57

to make eye contact at the moment. Can't think for

16:59

the

16:59

life of my house. Weighing in at 87.8. Great,

17:03

thanks James. Loaded. So do you

17:05

need to do some number crunching now? We've

17:07

got all of your data, thanks so much for that. We've

17:10

got three sets of data. Okay, I'm

17:12

going to go get a glass of water while you do all that work, if

17:14

that's okay. You go for it. Don't feel sorry for me.

17:21

So Damien, you've

17:23

got the results, I can't wait. Okay, James,

17:26

the scores on the doors. So we'll

17:28

start off with how much volume

17:31

you lost, how much... I sweated off. You

17:33

sweated off. So you sweated off 400 Nls,

17:36

so just short of half a litre in

17:38

less than an hour, just sitting there doing nothing.

17:41

Your heart rate went from 54 beats

17:44

per minute at 21 degrees

17:46

centigrade, that's the control. It

17:48

went up to 81 beats per minute

17:51

at 35,

17:51

and rose further

17:53

to 87 beats per minute at 40

17:56

degrees centigrade. That's like I'm actually

17:58

exercising. Quite a big rise.

17:59

Your blood pressure was well defended throughout,

18:02

so your blood pressure was absolutely normal and

18:04

that's a good sign here. The cardiac output, which

18:06

is the volume of blood

18:08

circulating around the body, it

18:10

increased from 5.9 litres per minute to 6.8 litres

18:12

per minute at 40 degrees centigrade, mostly because

18:18

of the increase in the heart rate. Okay,

18:20

so why is the heart rate going up then? It's

18:22

looking to increase

18:24

the circulation of blood around the body

18:27

because, don't forget, the convective

18:29

heat loss, getting that

18:29

blood to the skin surface and

18:32

the vasodilation to try to get rid of the heat

18:34

is a key factor. You were ventilating

18:36

more, so in terms of litres per

18:39

minute, you went from 9 litres per minute

18:41

at 21 degrees centigrade to 17, so you

18:43

almost doubled. I'm breathing twice as hard.

18:46

Twice as hard. I felt like I was just doing

18:48

calm, relaxed breathing the

18:50

whole time. Because you're breathing more, you were blowing

18:53

the carbon dioxide off. The direct effect

18:55

that has is it causes a smooth

18:57

muscle around the arteries of the brain that

19:00

supply blood to the brain. They

19:02

constrict, they get a bit tighter. And

19:05

as a consequence, we saw a reduction in flow.

19:07

There's less fuel getting to my brain than as that rises.

19:11

So am I more stupid when it's hot? Good

19:14

question. I wouldn't use the term stupid,

19:16

I would probably say how does short-term memory

19:18

do. No difference between 21 degrees

19:20

and 35 degrees, but we started

19:23

to see the numbers drop at 40 degrees

19:25

centigrade. In terms of the word recall, you

19:28

went from 23 corrects to 17

19:31

at 40 degrees centigrade. So that seems

19:34

to be the tipping point between 35 and 40. My

19:37

body's big goal throughout all of this is to preserve

19:39

my core body temperature so that I don't basically

19:41

cook my heart and liver and lungs

19:43

and stuff, isn't it? Exactly. So

19:45

what happened to my core temperature? Core temperature

19:48

is maintained. A couple of degrees around that 37

19:50

degree set point. You did feel uncomfortable, but

19:53

the body is working really quite nicely

19:55

to try to defend and maintain that core temperature,

19:58

to maintain blood pressure, to... maintain

20:00

flow to the brain, but of course the numbers

20:02

are suggesting you weren't the same beast

20:05

at 40 degrees as you were

20:07

at 21 degrees. And that's in less

20:09

than an hour. And would that get worse if

20:12

I was in here all day? Yeah, for

20:14

sure. And if you were replacing those fluids,

20:17

it would get very much worse. I remember

20:19

last summer it felt like it went on for weeks. What's

20:23

the difference? It becomes cumulatively

20:25

that much tougher. It's a bit like saying, you

20:27

know, I'm going to run a 10K, but I'm

20:29

going

20:29

to run a marathon. The world's apart,

20:32

you know, and the physiological stress

20:35

is very, very different. Now, Damien, we

20:37

did all of these experiments at 50% humidity,

20:40

but humidity is really important because it affects your ability to sweat,

20:43

doesn't enter to lose the heat that way. So

20:46

I was catching up with some researchers that basically

20:48

did lots of experiments like this, comparing

20:50

different heats and different humidities to find

20:52

out what they thought was like the

20:55

problematic combination of the two.

20:57

So take a listen to this.

21:03

Hello, I'm Rachel Coddle.

21:05

I'm a PhD candidate at Penn State

21:07

University. Rachel, thank you for coming on Inside

21:09

Health. Thank you for having me. I suppose we should

21:11

explain, first of all, what is

21:14

humidity and why does it matter

21:16

in terms of how our body responds to heat?

21:18

Humidity is the amount of water

21:21

that's in the air and it matters because

21:24

during heat stress, one of the main

21:26

ways that we cool our bodies is through

21:28

sweating and the evaporation of that sweat.

21:31

The more humid the air is, the less likely

21:33

we're able to evaporate that sweat

21:35

from our body. So when it's more humid

21:38

out, we lose one of our main mechanisms

21:40

to cooling our body. And so our core temperature

21:43

rises faster and puts

21:45

us at greater risk for heat-related illnesses.

21:47

So in the experiments I've been doing,

21:49

Rachel, we've kept the humidity constant

21:52

and we've been playing around with the heat to see

21:54

what it does to my body. But you've been trying to work

21:56

out what's that dangerous combination of

21:58

heat and humidity.

23:54

particularly

24:01

large or high or scary

24:03

temperatures. These environments

24:05

that we're seeing as our critical limits are

24:07

happening over the globe right now. Not

24:10

only are these heat waves becoming more frequent,

24:12

longer in duration and more severe but they're becoming

24:14

more humid which is creating a greater problem.

24:17

And this is happening now, Rachel. In 2022,

24:19

India and Pakistan were hit

24:22

with a severe heat wave. Temperatures

24:24

were higher than these critical

24:26

temperatures and humidities that we've seen. It's

24:29

definitely a now problem, not

24:31

a future problem that we're seeing.

24:33

There seems something kind of almost sad about all

24:35

of this that I can imagine 20 years ago,

24:38

the kind of research that you're doing would have all been

24:41

about extreme sport or athletes

24:43

or expeditions and adventures and all that

24:45

kind of stuff. And now it's very

24:48

much about the

24:50

changing face of our planet and the conditions people

24:52

are living in already.

24:53

Yeah, exactly. And the fact that

24:55

so many people die during these

24:58

extreme heat waves, honestly,

25:00

most of these deaths can be prevented,

25:03

especially with proper cooling strategies

25:05

and just general awareness

25:07

of the public of who's at

25:09

risk and what to do during these heat waves.

25:12

Rachel, thank you so much for coming on the program. Hey,

25:14

you're welcome. Thank you again for having me. So

25:18

what did you make of that? There's a whole gamut

25:20

of physiological stresses

25:23

that are going to challenge us as time goes by. And

25:25

there's a very strong argument that our physiology

25:27

is going to have to change quite aggressively to

25:29

cope with these environmental stresses because it's

25:31

changing so rapidly. So when

25:34

we're trying to answer the question of kind of like how hot is

25:36

too hot for the human body, is

25:38

there an easy answer to that? The

25:40

way we respond to heat is very individual.

25:43

So it's very difficult to say. When

25:45

the core temperature rises, you're

25:48

going

25:48

to about 37.4 degrees centigrade,

25:50

but people that are getting increasingly

25:53

hot, they can't find a cool place.

25:55

They're not replacing fluids. If the core temperature

25:57

rises to about 39.5 degrees, centigrade,

26:01

you know, they become what we call syncopated, very

26:03

light-headed, very dizzy, very

26:05

prone to fainting and again

26:08

the reason for that, they're not getting enough blood. I think

26:10

I've had that once. Yeah, so

26:12

it's pretty miserable. Once the core

26:14

temperature rises to around about 42 degrees

26:16

centigrade, of course, this

26:19

is where we start to see really, really

26:22

significant problems and if not

26:24

treated, you know, the individual will actually die

26:26

as a result of, you know, they've succumbed to, you

26:28

know, to the heat, to hypothermia.

26:29

Lots of people may be

26:32

listening to this programme thinking, I used

26:34

to go on a nice foreign

26:36

holiday in those kinds of temperatures, why

26:38

are you talking about that

26:40

as though it's a scary thing I used to celebrate going

26:43

on holiday in that kind of temperature? You're gonna leave

26:45

the lab today with a smile on your face. All

26:47

of your statistics coming through in terms of integrated

26:49

physiological response are telling me that you have

26:52

risen to that challenge and you've beaten that

26:54

challenge and you've done a jolly good job. That's

26:56

fair a thought for the older people that are

26:58

less physically conditioned, people

26:59

that are suffering from disease, you

27:02

know, patients with congestive heart failure, lung

27:04

failure, you know, patients that are

27:06

diabetic, patients with dementia or

27:08

Alzheimer's, that, you know, every

27:11

day it's a battle, it's a physiological

27:13

challenge for them. Now when you throw in

27:15

an extra-stricer, heat and humidity,

27:18

you know, sometimes they can't rise to that challenge.

27:20

Damien,

27:24

do you have any top tips for

27:26

coping with the heat? You know, keeping it simple

27:29

really, James, to me is key. As you

27:31

saw yourself, you've lost 400ml there over less

27:33

than an hour. It's not just

27:35

a case of just quickly drinking 400mls of water,

27:37

you know, it's about

27:39

slowly drip, drip, drip feeding to

27:41

maintain that. Try not to grab doors, certainly

27:44

try not to exercise in the

27:46

hottest part of the day. Another tip as well is

27:48

try not to get sunburned. Even a mild sunburn

27:51

can knock out the ability to thermoregulate or

27:53

to sweat,

27:54

you know, functionally sweat for up to as long

27:56

as two weeks. So... Two weeks? I've

27:58

never heard of that. Which is worse?

27:59

So the evidence is suggesting

28:02

there are more excess deaths as a result of the cold

28:04

snaps relative to the heat

28:06

waves that we see. But of course with

28:09

time, we're not really sure how

28:11

these things are playing out because we are seeing clear changes

28:13

in the climate. If we get hotter summers and milder

28:15

winters. Exactly. David, thank you so much for

28:17

having me. Lovely to see you, James. And

28:20

yeah, look forward to you coming back.

28:24

Well, I've come

28:26

back to Cardiff Bay because

28:29

I'm a little bit tired after all those experiments this morning. The

28:31

fatigue has really set in now. I

28:34

couldn't believe the difference between 35 and 40 degrees. I

28:38

thought I was coping really well. Then it got

28:40

really hot. So I'm just cooling

28:42

my body off now, enjoying the breeze. And

28:45

all I can do is wish you a nice

28:47

cool summer. I think

28:49

I'm going to go get myself an ice cream.

28:55

Hello, I'm Dr Michael Moseley.

28:58

And in my new BBC Radio 4

29:00

podcast, Stay Young, I'm investigating

29:03

some simple, scientifically proven things

29:05

you can do to rejuvenate yourself from

29:08

the inside out. Which will you

29:10

try? Maybe a slice of

29:12

mango to reduce your wrinkles. Delicious.

29:16

Or learning something new to stay sharp.

29:18

Hi, OK. Hi,

29:20

OK. How about lifting

29:22

some weights to protect your muscles against

29:24

the ravages of time?

29:26

That was quite

29:28

tough.

29:29

To hear all about how to stay young,

29:32

subscribe to the podcast on BBC

29:34

Sounds.

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