In this Festive edition, the best combinations of food and drink to avoid indigestion over the Christmas period, safer ways to grill meat and we reveal if lightweight, carbon fibre bikes really are the fastest option. We also look back over 2010 to to remember some of the years key scientific developments, including the domestication of fruit trees across of Africa and the increase of western diseases due to urbanisation. Plus we find out what makes someone photogenic, in Question of the Week!