This is the first episode in the second series.  I start my consultant career in Sheffield. On my first ward round I meet a mother who has just lost her child with what is thought to be cerebral palsy.  This leads to a diagnostic odyssey which results in diagnosis of a very rare condition known as Aicardi Goutières syndrome - I introduce you to this child's brother and, subsequently, his sister both of whom have the same condition.  We see the impact of this diagnosis on the family and learn how they support the affected children.