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Inflammation, from a cardiologist's viewpoint, refers to the body's complex biological response to harmful stimuli, such as pathogens, damaged cells, or irritants, aimed at removing the cause of cell injury, clearing out necrotic cells and tissues damaged from the initial insult, and initiating tissue repair. In the context of cardiology, inflammation often plays a pivotal role in the development and progression of various cardiovascular diseases.

Chronic inflammation, particularly in blood vessels, is implicated in the pathogenesis of atherosclerosis, where the arterial walls become inflamed due to the buildup of fatty deposits and immune cell infiltration. This inflammatory response contributes to the formation of plaques that narrow the arteries, leading to reduced blood flow and potentially causing heart attacks or strokes.

Inflammatory markers like C-reactive protein (CRP) and interleukins are often monitored in cardiovascular assessments to gauge the presence and severity of inflammation, aiding in risk assessment and treatment strategies for cardiovascular diseases. Managing inflammation is increasingly recognized as an important aspect of preventing and treating heart conditions, emphasizing lifestyle modifications, medications, and targeted therapies to mitigate its detrimental effects on the heart and blood vessels.