Podchaser Logo
Home
Why is everyone getting food allergies?

Why is everyone getting food allergies?

Released Wednesday, 19th October 2022
 2 people rated this episode
Why is everyone getting food allergies?

Why is everyone getting food allergies?

Why is everyone getting food allergies?

Why is everyone getting food allergies?

Wednesday, 19th October 2022
 2 people rated this episode
Rate Episode

Episode Transcript

Transcripts are displayed as originally observed. Some content, including advertisements may have changed.

Use Ctrl + F to search

0:04

This

0:04

episode is supported by cabinets

0:06

to go. For lots of people, the kitchen

0:09

is the most important part of their home.

0:11

If that's you, cabinets to go wants

0:13

to help you create a kitchen that you actually

0:15

want to spend time in. You may have seen

0:18

them on HGTV's dream

0:20

home. But in case you haven't, they've got

0:22

two hundred thousand cabinets available and

0:24

ready to ship, So you can cut down on

0:26

waiting time and get to installing.

0:28

Right now, you can get a full custom three

0:31

d design of your new WOW kitchen

0:33

at cabinets to go

0:34

dot com slash vox.

0:43

This podcast is brought

0:45

to you by amp, the new live radio

0:47

app that's changing the way people discover music.

0:50

Amp features a ton of live radio shows covering

0:53

hot new music, culture, and so much

0:55

more. It's the content you didn't know

0:57

you needed, all curated by real people,

0:59

not out algorithms. It's raw, it's

1:01

unfiltered, and it's easy to create your own

1:03

show for wherever, right from your

1:05

phone. Download today on the app store

1:08

or just ask Alexa to play amp. Visit

1:10

on AMP dot com to

1:12

learn more.

1:18

Meghan crews grew up eating tons

1:20

of shellfish. I'm

1:22

from Shreveport, Louisiana. So

1:25

we have lots of crawfish. and

1:27

seafood, and all the

1:30

shrimps.

1:30

And she particularly loved

1:32

it on special occasions.

1:34

So for my 21st birthday,

1:36

I decided I would get all the seafood. So

1:38

that's what I did. Go pick out

1:40

all my blue crabs I'm so excited.

1:43

We have, like, five pounds.

1:44

Meghan boiled the crabs in some water

1:46

with a splash of orange juice and

1:48

sat down to eat with her husband.

1:49

I was sitting there eating my crab.

1:52

Totally everything was fine. I was happy. I

1:54

have my daggers living my best

1:56

life. but pretty

1:57

soon she started feeling kind of

1:59

weird. I started

2:01

getting really edgy for a second

2:03

and then I think I went to go pee And

2:05

then

2:05

when I went to go pee, I'd like pulled

2:07

down my pants and there's welts all over my

2:09

legs and all over my

2:11

body. And I realized that something

2:13

was wrong. And so

2:15

I was like, I'm gonna take a shower. That seems

2:17

like a good option to do. Turns out you're

2:19

not supposed to take a shower. because then everything

2:22

started to get worse. And

2:24

then I, like, came out to my husband. He was

2:26

like, why do you look like that? And I'm

2:29

I don't know why I looked like that. Why am I turning

2:31

purple? What is going on?

2:33

They didn't know what to do, so they decided

2:35

to get to the hospital as fast as they could.

2:38

he's like past these lights.

2:40

I was feeling really light headed and I felt like I

2:42

might pass out, but I was also terrified to

2:44

pass out because I was like, what if

2:46

I don't get to the hospital in time?

2:47

They finally got there

2:49

and it was basically a ghost town.

2:51

It's like midnight. It's the graveyard

2:53

shift. No one really wants to be

2:55

there. And then I'm getting admitted, and I'm just

2:57

trying to, like, I, like, walk up to the

2:59

lady, and I'm just, like, hi,

3:01

I think I'm having anaphylaxis, like,

3:04

almost blue in the face, but also in

3:06

panicking

3:06

on top. Anaphylaxis

3:08

is a full body response to an allergy.

3:11

symptoms

3:11

can be different from person to person,

3:13

but typically the throat's wells

3:16

making it hard to breathe, blood pressure

3:18

drops, and the heart rate shoots up.

3:21

people

3:21

can die from it. And when the doctors

3:23

finally saw Meghan, they were

3:24

floored. So

3:26

then they called the med students in because they

3:28

were like, this is the worst thing we've seen

3:30

the worst case of anaphylaxis. I'm

3:32

like, come Let's go. You know, it's

3:34

my birthday. It's a party at this point. Right?

3:36

The nurses eventually got some epinephrine. That's

3:39

the stuff in an EpiPen. And they gave

3:41

it to Meghan through an IV to stop

3:43

the anaphylaxis.

3:44

My doctor asked me, he was like, so what'd you

3:46

eat? And then I told him, and he's like, oh, shellfish.

3:48

Well, how often do you eat that? I'm like, all the

3:51

time. So he was like, well,

3:53

I'm guessing that's probably what caused it,

3:55

but it was just very odd because I've ate it my

3:57

whole life.

3:58

Meghan couldn't remember having food allergies

3:59

at all as a kid. I don't

4:01

I can't even tell you how much random stuff I ate.

4:04

I never died then.

4:05

And now Meghan's not just allergic to

4:07

shellfish. She can't eat peanuts

4:09

anymore or garlic. or

4:11

a whole bunch of other foods used to love.

4:13

I had relatively twenty two allergies

4:16

erupt around the age of twenty

4:18

one.

4:19

But Meghan's not the only

4:21

one who's more allergic than she used to be.

4:23

According to allergist Scott Citra,

4:25

more and more people Both

4:28

kids and adults are developing

4:30

allergies. Come on. You know, if

4:32

you're someone who's over the age of forty

4:34

or so, you were a kid in

4:36

school your friends

4:38

didn't really have food

4:40

allergies. You have kids now. Oh

4:42

my gosh. You know, like several kids in the

4:44

classroom have food allergies. I mean, sort of like a,

4:46

you know, you don't have to be a scientist to say,

4:48

hey, wait a minute. It's not really a question that

4:50

there has been an increase. The question

4:52

really is why? I'm

4:55

no. I'm Hassonfeld. And this week, I'm unexplainable.

4:58

Why are so many more people getting

5:00

food allergies? and is there

5:02

anything we can do about it?

5:17

Okay.

5:19

Umer Erfan. Hello, no. You've

5:21

been reporting on the rise

5:23

in allergies for vox. Before

5:26

we get to the rise itself and what's

5:28

going on over there, Let's make sure we just have

5:30

our basic concepts in order

5:32

here. What exactly is an allergy?

5:34

An allergy is like a false alarm in the

5:36

immune system. It involves a very particular

5:38

mechanism that scientists think that we evolve

5:41

to help us deal with parasites. Mhmm.

5:43

These are things like roundworms and hookworms.

5:45

But occasionally, it seems like the immune

5:47

system can get confused. It can go from targeting

5:50

parasites to targeting peanuts. And

5:52

then as a result, the immune system starts

5:54

doing all these things that can actually be harmful

5:56

to you. So I talked to Scott Stittura

5:58

about this who we heard from at the top. He's a pediatric

6:00

allergist at the Mount Sinai School

6:02

of Medicine. and he told me that the responses

6:04

can range widely from things like

6:06

rashes and hives all the way up to anaphylactic

6:09

shock, and that can send you to the emergency room.

6:11

it's totally counterproductive. I mean, why should

6:13

I be eating something? And I all of a sudden swell

6:15

up, can't breathe? You know, that seems kind of

6:17

ridiculous. but this is the

6:19

same system, the same immune components

6:22

that fight parasites. So

6:24

you're basically saying that an

6:26

allergy may have

6:28

developed in response to something that is

6:30

actively harmful. But at this point, you know, with

6:32

something like peanuts and shellfish, someone

6:34

going into anaphylactic shock from,

6:37

say, Showfish is really

6:39

just their body turning on itself.

6:41

Well, not the body turning on itself. That would be an

6:43

autoimmune disease. Okay. This is a body turning

6:45

on an

6:46

outside source of

6:48

an allergen

6:49

that is otherwise benign. So

6:52

autoimmune diseases actually have a slightly

6:54

different mechanism. Okay. With an allergy, your body is

6:56

turning on something that's foreign to it,

6:58

but benign. And that's because your

7:00

immune system has this very delicate task

7:02

tried to sort what is part of you and what

7:04

is not part of you, but they also have

7:06

to sort the gray area as well. These are

7:08

the things that are not part of you, but harmless

7:10

and these are things that are not part of you that

7:12

are harmful. And so the immune

7:14

system learns to recognize dangerous

7:17

pathogens and ones that can live

7:19

with us and may actually be beneficial to our

7:21

immune system. And that's actually a

7:23

little bit trickier. And in that gray

7:25

area, that's where the immune system can

7:27

get scrambled. And that's where we

7:29

see allergies arise. They start overreacting

7:31

or start treating something as harmful, that

7:33

is otherwise actually harmless.

7:36

though So if peanuts

7:37

are harmless, like, how does the body start

7:39

getting tricked into thinking that they're harmful?

7:42

Like, how do you actually start getting allergic

7:44

to peanuts or shellfish or something like that?

7:46

Right now, we don't really have a good answer for that,

7:48

and scientists are hard at work trying to find

7:50

out. It's an important mystery because

7:53

we're finding that more and more people

7:55

are becoming allergic. to peanuts and to

7:57

shellfish. And they're having some very severe

7:59

allergies so that health burden from allergies

8:01

is actually increasing. So how

8:03

much have allergies actually

8:05

gone up recently? The conventional

8:07

wisdom here in the US, maybe going back to the

8:09

nineties, was that in textbooks you'd

8:11

see that about four percent of kids had

8:13

food allergies, maybe two percent of adults. the

8:15

thinking was that kids would grow out of their allergies

8:17

as they got older. But now,

8:20

the studies from the US and other

8:22

locations are saying that it's more like

8:24

eight or ten percent of children

8:26

and around the same percentage

8:29

for adults. So so a

8:31

little bit higher in kids and like a lot

8:33

higher in adults. That's right. And, you know,

8:35

in some instances, we're talking about on

8:37

average, you know, roughly one in

8:39

every thirteen kids has a foodborne

8:41

allergy. Oh, that's like two kids per

8:43

every classroom. So when we're talking

8:44

about allergies going up, do we know if this

8:46

is more people being born with allergies

8:49

or or more people developing allergies

8:51

over time? It

8:52

seems to be a mix of both. Okay.

8:54

Doctors are finding that more children

8:57

are being diagnosed with allergies

8:59

as babies and as toddlers and

9:01

so on. but more adults are

9:03

also reporting that they're becoming sensitive

9:05

to foods, that they weren't sensitive

9:07

to before. So it seems like we're

9:09

seeing both an increase in people

9:11

born with allergies and people acquiring

9:13

allergies later in

9:14

life. Do

9:17

scientists have any idea at all?

9:19

Why this is happening? Like, why

9:21

allergies are going up so much? Well, one of the

9:23

best guesses and the one that seems to have the

9:25

most Support behind it is this idea called the

9:27

hygiene hypothesis. Okay. You

9:29

know, remember how I said earlier that this was a

9:31

mechanism in your immune system that used to deal

9:33

with parasites. well, as we've

9:35

developed this society in the

9:37

US and around the world, as we've

9:39

improved sanitation and, you know,

9:41

spending even less time outdoors, we're

9:43

less likely to be infected by parasites.

9:46

You start living in houses. You

9:48

start being able to protect

9:50

yourself with antibiotics, with vaccines.

9:52

you start eating food that is clean.

9:54

It comes in a can. You're using a

9:56

dishwasher that really cleans every

9:58

speck of dirt from your

9:59

dishes. and your immune system is seeing a

10:02

very different pattern of

10:04

bacteria.

10:05

And so without these opportunities to

10:07

be infected, this part of the immune

10:09

system stays revved up in some people,

10:11

and then it can turn on more innocuous

10:14

things. For example, the

10:16

danders in our pets or the pollens in our

10:18

air or in this case the

10:20

proteins that are in our foods. And

10:22

so we've seen allergies rise

10:24

with development in countries as sanitation has

10:26

improved. We see lower rates of allergies

10:28

in people who live in rural areas, but higher

10:30

rates in people who live in urban areas.

10:32

Mhmm. so there seems to be this very

10:34

strong association with

10:36

a heightened level of cleanliness and

10:38

sanitation and allergies. This is like the

10:40

general idea behind, I assume

10:42

parents who wanna be like, oh, we have a kid, like like to

10:44

put him on the subway and have him like a

10:46

pole. I mean, don't like a subway poll

10:48

that's gross for a number of reasons beyond

10:51

allergies. But, yeah, there is this idea that

10:53

maybe living in a less hermetically

10:55

sealed environment early in

10:57

life may be beneficial. Mhmm.

10:59

And now more scientists are actually

11:01

advocating for a graduated

11:03

and deliberate way of exposing

11:05

infants and toddlers to potential allergens.

11:07

But if hygiene

11:09

theory is responsible for the rise in allergies

11:12

here, like, why is this only

11:15

happening now. It's not like we didn't have

11:17

sanitation in the nineties. You're

11:19

right. Sanitation has been improving

11:21

for hundreds of years, and we've been seeing this in many

11:23

parts of the world. So why are we seeing

11:25

such a big pick up now in the past

11:27

twenty to thirty years? That's not

11:29

entirely clear. And for something like allergies,

11:31

it's pretty likely that there are multiple

11:33

factors at work here. So even if the hygiene

11:35

hypothesis seems to be the strongest

11:37

theory, there might be some other element

11:39

that is playing a role here as well.

11:41

So

11:42

if this hygiene theory doesn't explain the rise

11:44

in allergies on its own what are

11:46

some other factors that might be contributing

11:48

here? One idea that scientists are looking

11:50

into is the timing of

11:52

food exposure. Okay. For instance, this idea that

11:54

perhaps if a baby is vulnerable to developing

11:56

allergies, they should not be exposed to

11:58

foods that could potentially trigger those allergies

12:01

Don't give that baby milk protein

12:03

until age one, egg until age

12:05

two, peanuts, tree nuts, and fish

12:07

until age three.

12:08

And that

12:09

was well intention, but it didn't have a lot

12:11

of research behind it. But now the thinking

12:14

has almost completely reversed. that if you

12:16

are at higher risk abilities, it might be a

12:18

good idea to expose these babies on a

12:20

very slow graduated basis deliberately

12:22

early in life. ingesting the

12:24

food lets the gut immune

12:26

system see it and

12:28

learn about it in a positive

12:30

way. Like, this is something that's nourishment

12:32

for me. and that will help desensitize

12:34

them. Whereas if you're not eating it,

12:36

it's still in the environment, meaning that there's

12:38

still milk in the environment, there's still egg in the

12:40

environment, there's a peanut around you,

12:42

all of those proteins that should have been in your

12:44

mouth are instead all around you and on

12:46

your skin, and it's hyping

12:49

up an immune response that's counterproductive.

12:52

Then if you were waiting until you're one

12:54

or two to eat it and you then

12:56

ate it, it's too late. Your immune system

12:58

already learned to fight that protein that

13:00

it should have learned to accept by eating

13:02

it early on. And so that's one

13:04

other theory is that the timing of when we're

13:06

exposed to certain types of foods and

13:08

allergies of potential threats

13:10

is changing in the modern world. And if

13:12

we change the timing of that exposure, that

13:14

could help counteract that trend. So

13:16

it seems like hygiene theory

13:18

combined with some of

13:20

this timing of food exposure could

13:22

explain a lot of this rise in allergies.

13:24

Are there

13:25

reasons to be skeptical of both of these

13:28

theories together? I

13:28

mean, they do seem to explain a lot, but they don't again

13:31

explain everything. What do you mean?

13:33

Well, for one thing, why are adults then

13:35

developing allergies as well? Right?

13:37

Adults and children sometimes are becoming

13:39

sensitized to the same things. So

13:41

what what does that work there? Is there

13:43

a common environmental exposure

13:46

for instance? that might be making people

13:48

more vulnerable to allergies. Yeah. It seems

13:50

like hygiene theory and food exposure

13:52

are

13:52

all about kids

13:53

having allergies. Are there any

13:56

ideas about, you know, what's behind

13:58

this rise in adult onset allergies?

14:00

That's also a big mystery. there's

14:02

a few ideas that scientists are studying

14:04

as well. One is this idea that

14:06

perhaps in a post infection

14:08

state, like maybe if an adult got sick with the

14:10

flu or some other serious illness. In

14:13

that period after the infection,

14:15

their body's immune system might

14:17

be recalibrating. and in

14:19

that phase end up targeting something

14:21

that is otherwise harmless. By

14:23

post infection state, you mean sort of like

14:25

after COVID or someone that might

14:27

have long COVID like these lingering symptoms?

14:29

That's right. You know, even with influenza

14:31

and many of these other common infections

14:33

that we see We're starting to

14:35

appreciate more that they can actually have symptoms that

14:37

last for a long time even after

14:39

the virus or the bacteria that caused the

14:41

illness has been defeated by the body. Perhaps

14:43

that's playing a role in adult onset allergies

14:45

as well. Like, maybe you had an illness, you

14:47

got better, but your immune system in

14:49

that phase got redirected

14:52

into targeting something that

14:54

really it shouldn't be targeting. But

14:56

beyond that, I mean, I think scientists are trying to be

14:58

open minded here and just see what else is

15:00

at

15:00

play. So we've

15:03

got all these possible explanations

15:05

here. What makes

15:07

this so complicated

15:09

to solve? Like, what are scientists still

15:12

wrestling with? For one thing, it's

15:14

really hard to isolate any one of these

15:16

variables because, you know, we we talk about allergies.

15:18

They do individuals, but when we're talking about the rise in

15:20

allergies, we're talking about something that's

15:22

happening across tens of thousands, if not millions of

15:24

people. And there are so many different other

15:26

variables that are at play as well.

15:28

you know, the environment that they live in, their genetics

15:30

susceptibility, other kinds of environmental

15:32

exposures, other kinds of sociological

15:34

exposures as well. So scientists want to

15:36

have a little bit of humility here and

15:38

say that, you know, we don't fully grasp all

15:40

the things that are at play when it comes to

15:42

these allergies.

15:48

After the break, just how

15:50

allergic are we gonna get?

15:52

Is everyone gonna get allergic

15:54

to everything? That's

15:56

coming up next.

15:59

This is

15:59

advertiser content brought to you

16:01

by AbbVie. We're

16:03

always trying to understand

16:05

how do we stop disease. Right?

16:07

Disease comes in. We try to stop it. That's

16:09

how we practice medicine. An

16:12

interesting thought would be,

16:14

what if we actually didn't get

16:16

disease? What

16:18

if we prevented disease?

16:21

Hi. My name is Howard Jacob. I'm a vice

16:23

president at AbbVie. I've

16:25

had the Genomic Research Center and

16:27

I also had our data integration

16:30

across r and d. Better medicine

16:32

starts with better information.

16:33

So Howard and AbbVie have been setting

16:35

a collection of

16:36

more than one million human genomes to advance

16:38

our understanding of disease. It's

16:41

a large amount of data. Your DNA

16:43

extended end to end from all of your

16:45

hundred trillion would go to the sun

16:47

and back six hundred and sixty

16:49

six point five times.

16:51

All of that genetic information will have

16:54

major

16:54

implications for the future of healthcare.

16:56

helping doctors tailor treatment to every

16:58

patient's needs. For many

17:00

genes, there are tests where you can actually say,

17:02

oh, this is the dose you should take. This

17:04

is when you should take it and this is why you're taking it. It

17:07

opens the door for prescribing medications

17:10

differently and at different doses for

17:12

each individual. Their work is

17:14

already saving lives, but genetic

17:16

researchers are far from satisfied. I

17:19

just know that we can do more. I know we

17:21

can enable physicians medicine

17:23

better. I know we can able patients

17:25

to live healthier lives. I know we

17:27

can develop better therapies and we just have

17:29

to do it. To learn more

17:31

about how AbbVie is shaping the future of medicine,

17:34

visit here now dot ABBIE

17:38

Fox

17:40

Creative.

17:42

This is

17:43

advertiser content from Amazon Ads.

17:46

Take

17:47

another deep breath in and

17:50

on exhale,

17:52

relax your shoulders.

17:54

I

17:55

think this meditation series

17:57

is really hoping.

17:59

The brick sculpture

18:01

is coming to a city here. are

18:03

you?

18:03

Seriously. A misplaced

18:05

ad can really ruin an experience.

18:07

According to research commissioned by Amazon

18:09

Ads and Omnicom Media Group, sixty

18:11

eight percent of consumers for ads that are relevant the content

18:13

they're embedded in. It can be important for brands

18:15

to be part of the experience, not

18:18

interrupted. And Amazon Ads, we make it

18:20

easier for brands to reach the right audience.

18:22

Like when they're listening to Amazon Music's ad supported tier on

18:24

an Alexa enabled device,

18:26

getting you more of this.

18:28

Coming Essential's

18:29

Lavery Joy promotes

18:32

relaxation and melts your stress

18:34

away. Just say, Alexa,

18:36

add to cart. to

18:38

have calming essentials lavender oil delivered to your door.

18:41

Alexa, add to

18:42

cart. Learn more

18:45

at

18:45

vox dot comm slash museum of modern

18:48

ed.

18:56

Humira, we're

18:58

back. Hey, Nom. So

19:00

how should I wrap my head around exactly

19:03

how bad this rise in allergies is.

19:05

Like, are we all gonna just get

19:07

more and more allergic until

19:09

everyone has allergies? To answer your second

19:11

question first, the answer

19:13

is no. scientists don't think that

19:15

we're all going to get allergies. And if

19:17

you don't have allergies right now, the researchers

19:19

that I talked to told me that you really

19:21

shouldn't lose sleep about it. Most

19:23

people don't develop allergies as adults.

19:25

And the ones that do, they're just

19:27

one part of this rise in overall allergies

19:30

we're seeing in the population. Now,

19:32

while allergy rates are going up,

19:34

it does appear that in some circumstances that

19:36

it's reaching a plateau, it seems to be leveling off when

19:38

it comes to certain types of foodborne allergies.

19:41

And that sort of indicates that there might be

19:43

just an upper limit to how many people in

19:45

the population are susceptible to developing

19:47

allergies. So, for getting to this plateau, why

19:49

should we be worried? Is the

19:51

problem just kind of solving itself?

19:53

A plateau

19:54

means that it's

19:55

staying level. It's not going down. We're

19:58

talking about close to thirty three million

20:00

people in the US having food allergies.

20:02

That's about one in ten people.

20:04

So even if that rate holds steady, right now, that's

20:06

a huge health burden, especially for families

20:08

with kids. You know, that cost them about twenty

20:10

five billion dollars per year.

20:12

And not only that, like, your quality of life goes down, like,

20:14

imagine being paranoid about

20:16

eggs being in anything because eggs are

20:18

used to make everything. soy

20:20

is used to make everything. Peanuts are used to make

20:23

everything. And again, people still die

20:25

from allergies as well, like people with severe

20:27

anaphylaxis do die.

20:29

It's not in huge numbers, but it can be fatal.

20:31

And knowing that that's a possible

20:33

outcome adds to the stress of dealing with

20:35

it. And, you know, we're talking everyone

20:37

from little kids to adults. And so this is a

20:39

pretty common experience that

20:41

is, you know, becoming increasingly more

20:44

common. And then

20:45

let's

20:46

just say you do develop

20:49

adult onset allergies or, you

20:51

know, if you're just one of the

20:53

unlucky children that seem to be born

20:55

with more allergies today? Like, what are you supposed to do?

20:57

Are these things that can be cured or

20:59

are these things that just have to be managed? Right

21:01

now, the big thing is management.

21:03

with foodborne allergies, I mean, the best thing is to

21:05

simply avoid the food. Yeah. In most

21:08

circumstances, just try not to eat

21:10

it. Beyond that, there are some experiments going on about

21:12

how to use techniques like

21:14

immunotherapy. Mhmm. And I talked to Richie

21:16

Gupte, this pediatrician and allergy research

21:18

at Northwestern University. and

21:20

she described this process by where you gradually

21:23

introduce somebody to a food that they're

21:25

allergic to over time in order to build

21:27

up a

21:28

tolerance. under an allergist supervision,

21:31

you slowly up dose

21:33

until you can tolerate, you

21:35

know, certain amount of peanuts. And

21:38

then you keep that amount in your

21:40

diet so that your body keeps

21:42

recognizing it. that would

21:42

sort of be like an allergy vaccination

21:45

almost like give you a tiny amount of peanut

21:47

and kind of vaccinate you against peanuts. Is that is

21:49

that a wrong analogy? I kind of I

21:51

mean, I mean, you are talking about, yeah, like, introducing

21:53

the immune system to something. But, like, with

21:55

a vaccine, you're teaching your immune system to fight

21:57

something. Whereas with this, you're trying to teach your

21:59

immune system, that it's harmless. That's really like a reverse

22:02

vaccine. Yeah. Basically. Yeah.

22:03

You're trying to basically, like, tell them to tell the immune

22:05

system, hey, this stuff is friendly. It's

22:08

harmless. don't overreact, take a deep

22:10

breath. Okay. But beyond that, there

22:12

isn't really that much to do because we don't

22:14

really know how to cure an

22:17

allergy per se. So if

22:19

there's no way to cure it, is there

22:21

any way to prevent being allergic to

22:24

something? There isn't as

22:26

far as we know for for adults. But

22:28

I mean, for young infants, it does seem like the

22:30

earlier exposure to certain types of allergens

22:32

does play a role. you know, there was

22:34

this study that was done in the UK called the

22:36

LEAP

22:36

study. It was a landmark study where their

22:39

theory was, okay, maybe if the

22:41

immune system sees this food in that

22:43

first year of life, they're getting used to it and they

22:45

don't have the allergy.

22:47

They did a randomized controlled

22:49

trial of infants and they exposed

22:52

them to peanut proteins. They found that incorporating

22:54

these peanut proteins into some of their food,

22:56

into their baby formula, in their

22:58

diet early in life, that led to a much

23:00

lower rate of peanut allergies. they

23:03

decreased their development of peanut allergy

23:05

by eighty percent. What's

23:07

exciting

23:07

about that is knowing

23:10

that if we counsel

23:12

new parents for their

23:14

babies correctly and they start peanut

23:16

products

23:16

and potentially other food

23:19

allergens, early in life, their immune system

23:22

recognizes it and does not

23:24

then go to fight it.

23:26

So that's a

23:27

part of the challenge here is figuring out what

23:29

to introduce babies to and when. And

23:31

if you can do that, then maybe you can

23:34

help stem this rise in

23:36

new allergic reactions in

23:38

kids. So is this are

23:40

we are we calling for, like, a peanut,

23:42

a maricore, like, mobilized, the

23:44

country get tiny amounts of peanuts to all babies across

23:46

the country? Not quite. You know, it's not as

23:48

though we can make a categorical recommendation

23:51

across the board because

23:53

allergies are very particular and very specific to

23:55

individuals. So while we are seeing a society

23:57

wide increase in them, the way they

23:59

manifest in individuals is very

24:02

unique. A lot of researchers say it's

24:04

worth getting diagnosed, to worth

24:06

actually seeing an allergist and figuring

24:08

out what your reaction was when you

24:10

have a bad reaction to a food, because

24:12

it may not necessarily be the case that you have to

24:14

avoid it forever. The

24:15

more you know about what you

24:17

have, you know, the more you know

24:19

how to manage it. So

24:21

when we've got this

24:22

collective public health problem that's

24:24

based on a bunch of hyper

24:27

individualized responses to

24:30

allergies, what

24:30

are we supposed to do? How are we supposed to solve a problem

24:32

like this? I mean, you can approach it

24:34

from multiple angles because like you said, this is the

24:36

a problem with has many

24:38

different routes and thus requires many different solutions.

24:40

And so one is, you know,

24:42

trying to inoculate the

24:45

individual, trying to make them desensitize

24:47

to them, to to the allergen to begin

24:49

with and trying to head off the allergy preventing it

24:51

from beginning. And then if they do develop an

24:53

allergy to minimize exposure, so

24:55

to sure that they're not being exposed

24:57

to something dangerous and to make sure that their symptoms

24:59

can be easily mitigated and that people

25:01

know, for instance, if they see a severe allergic

25:03

reaction, how to use an EpiPen.

25:05

if they do see somebody with an allergic reaction of

25:07

building a culture around that. So

25:09

if you see someone and they're turning purple

25:12

and they can't breathe and like you

25:14

know that they're not choking, Check them

25:16

for the EpiPen, and

25:18

do remember that it's blue to

25:20

the sky and orange to

25:21

the thigh. Meghan who

25:24

talked to us about her seafood allergy at the beginning

25:26

of the episode, she told me that going out

25:28

to eat makes her nervous that the

25:30

wrong exposure could land her in the

25:32

emergency room again. It's

25:33

like Russian roulette. You

25:35

never know. Something could happen. It's

25:37

a waiting game. In

25:38

the foreseeable future, allergies are here to stay, and we

25:40

might not know fully why these allergies are on

25:42

the rise, but to whatever extent that we can

25:45

mitigate allergies to

25:47

reduce their harm on individuals and help

25:49

the people with allergies live,

25:51

you know, productive, fruitful, and

25:54

like, non anxiety inducing lives, and then I

25:56

think that is a worthwhile endeavor.

25:58

No

25:58

one chooses to be allergic to a

25:59

whole bunch of things. I

26:02

promise, like, me and all my

26:04

friends, most of us didn't have our

26:06

allergies on set until we got older.

26:08

So it's not that we

26:10

don't miss cinnamon buns. It's not that we don't miss the Reese's

26:12

Pieces. It's not any of that

26:14

stuff. It's

26:14

that we can't for our health.

26:20

This episode

26:23

was reported by Umer Erfan and

26:25

produced by me,

26:26

Manning Nguyen. there

26:28

was editing from Katherine Wells, Brian

26:31

Reznik, Meredith Hodnot,

26:33

and Noah Am

26:33

Hassonfeld, who also wrote the music. Christian

26:36

Ayala did the mixing and the sound

26:38

design, Zoey Mullich, did the

26:40

fact checking, and somewhere deep in the

26:42

woods, Bird Pinkerton. found an

26:44

old key inscribed with an octopus. Additional

26:48

thank you to Alcistoides. If you

26:50

have any thoughts about this episode or ideas

26:52

for the show, please email us.

26:55

We're unexplainable at vox dot com, and we'd

26:57

also love it if you left us a review or

27:00

we're waiting. Unexplainable is part of the vox

27:02

media podcast network, and we'll be back

27:04

next week.

27:10

Laptops

27:11

on Intel V Pro and Intel

27:13

EVO design, let your team do their best

27:15

work wherever they work. with

27:18

all day real world battery life, quick charging,

27:20

and remote IT support. Working on the

27:22

go has never been so easy. How wonderful

27:24

is that? Visit intel dot comworks best

27:26

for details. Results may vary.

27:32

At

27:33

Amazon, better jobs today

27:36

mean more opportunities for

27:38

tomorrow. On top of receiving best in

27:40

class benefits, Employees have access to

27:42

nine career skills training programs.

27:44

That means over seven hundred and fifty

27:46

thousand employees can learn in demand

27:49

skills allowing them to

27:51

advance into higher paying jobs within

27:53

Amazon. For employees looking to further

27:55

their education, Amazon tuition

27:57

at over one hundred and eighty

27:59

institutions across the country. That

28:01

includes college degrees, high school

28:03

diplomas, GEDs, and ESL

28:05

certifications. Everything from classes to books is

28:07

paid for in advance so employees can

28:09

focus on building careers made for

28:11

tomorrow. Learn more at about

28:13

amazon dot com.

Unlock more with Podchaser Pro

  • Audience Insights
  • Contact Information
  • Demographics
  • Charts
  • Sponsor History
  • and More!
Pro Features